Riboflavin for Migraine

The nutraceutical Riboflavin has long been regarded as “just another vitamin” and all associated benefits have been contained within that arena. Only recently has this B vitamin been recognized for its effectiveness in treating several conditions, including migraine. That is why we make sure you get your daily does in every glass of Axon Relief. But what exactly is it? Read on to learn more.

What is riboflavin?

Riboflavin, or B2, is a water soluble vitamin that is found in many foods like green vegetables, eggs, dairy products, including milk, almonds, mushrooms, and meat. It has several primary roles, such as aiding the body in absorbing certain nutrients, breaking down food particles, and maintaining tissues. However, researchers have discovered that this vitamin’s benefits extend even farther, and it is a very effective component in migraine prevention.


Riboflavin has been the focus of several trials. In one of the most notable (J. Shoenen et al), the trial compared 400 mg of riboflavin to a placebo, both administered daily. The 12 week trial showed a decrease in migraine attack frequency of 2 per month (comparing month 4 to month 1). By month 4, 56% of the participants were experiencing a 50% reduction I the frequency of their migraines.

How to take riboflavin for migraine

The Canadian Headache Society (CHS) has set forth guidelines for using riboflavin for migraine. They advise taking 400 mg. per day. It may be taken in capsule form or as an additive to a food or drink. In the United States, many cereals and grains are fortified with riboflavin as required by law. However, supplementation may still be necessary.

Riboflavin has received a “strong recommendation” from the CHS for migraine prevention. The American Academy of Neurology (AAN) and the American Headache Society (AHS) have given riboflavin a Level B rating. They recognize its effectiveness and recommend considering it in the prevention of migraine.

Every glass of Axon Relief has a full 400 milligrams of riboflavin (along with some other really good stuff!). It’s a delicious way to start your day and help you have fewer migraine days.

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